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Article

Identification of molecular subphenotypes in two cohorts of paediatric ARDS.

Thorax - 18 Jan 2024

Yehya Nadir, Zinter Matt S, Thompson Jill M, Lim Michelle J, Hanudel Mark R, Alkhouli Mustafa F, Wong Hector, Alder Matthew N, McKeone Daniel J, Halstead E Scott, Sinha Pratik, Sapru Anil

Abstract excerpt

BACKGROUND: Two subphenotypes of acute respiratory distress syndrome (ARDS), hypoinflammatory and hyperinflammatory, have been reported in adults and in a single paediatric cohort. The relevance of these subphenotypes in paediatrics requires further investigation. We aimed to identify subphenotypes in two large observational cohorts of paediatric ARDS and assess their congruence with prior descriptions. METHODS:...

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Identifiers

PMID: 37813544
DOI: 10.1136/thorax-2023-220130
PMCID: PMC10850835

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