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Article

Circadian control of ConA-induced acute liver injury and inflammatory response via Bmal1 regulation of Junb

22 Jul 2023

Abstract excerpt

Background & Aims: Circadian rhythms play significant roles in immune responses, and many inflammatory processes in liver diseases are associated with malfunctioning molecular clocks. However, the significance of the circadian clock in autoimmune hepatitis (AIH), which is characterised by immune-mediated hepatocyte destruction and extensive inflammatory cytokine production, remains unclear. Methods: We tested the...

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PMID: 37791375
DOI: 10.1016/j.jhepr.2023.100856

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