Article
Single-cell transcriptome sequencing reveals tumor heterogeneity in family neuroblastoma.
Frontiers in immunology - 1 Jan 2023
Zhang Yunlong, Ma Yue, Liu Qingqing, Du Yifei, Peng Liang, Zhou Jianwu, Zhao Zhenzhen, Li Changchun, Wang Shan
Abstract excerpt
Neuroblastoma(NB) is the most common extracranial solid tumor in childhood, and it is now believed that some patients with NB have an underlying genetic susceptibility, which may be one of the reasons for the multiplicity of NB patients within a family line. Even within the same family, the samples show great variation and can present as ganglioneuroblastoma or even benign ganglioneuroma. The genomics of NB is...
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