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M1/M2 Macrophage Skewing is Related to Reduction in Types I, V, and VI Collagens with Aging in Sun-Exposed Human Skin

11 Aug 2023

Abstract excerpt

Sun-exposed, aged human skin is fragile because of collagen fragmentation and loss. We recently reported that the balance of M1 and M2 macrophages is associated with chronic inflammation and related inflammaging in sun-exposed human skin. In this study, we analyzed its role in the maintenance of collagen matrix formation by performing histological analyses of human facial skin. In addition, RNA sequencing,...

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Share to Contact Dermatitis and Allergies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37789949
DOI: 10.1016/j.xjidi.2023.100222

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