Article
M2 macrophages promote wound-induced hair neogenesis.
Journal of dermatological science - 1 Sept 2018
Kasuya Akira, Ito Taisuke, Tokura Yoshiki
Abstract excerpt
BACKGROUND: De novo hair regeneration occurs in scars of normal adult mice. This interesting phenomenon is termed as wound-induced hair neogenesis (WIHN). We hypothesized that M2 macrophages are crucially involved in WIHN. OBJECTIVE: To clarify the contribution of M2 macrophages to WIHN. METHOD: We established a mouse model of WIHN. A full thickness skin excision was implemented on the back of C57BL/6 (B6) mice....
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