Article
Tumor oncogene (KRAS) status and risk of venous thrombosis in patients with metastatic colorectal cancer.
Journal of thrombosis and haemostasis : JTH - 1 Jun 2015
Ades S, Kumar S, Alam M, Goodwin A, Weckstein D, Dugan M, Ashikaga T, Evans M, Verschraegen C, Holmes C E
Abstract excerpt
BACKGROUND: Patients with metastatic colon cancer (mCRC) are at increased risk of venous thromboembolism (VTE). Limited preclinical data suggest that the oncogene (KRAS) mutational status of the tumor represents a plausible clinical link to systemic hypercoagulability in cancer patients. OBJECTIVES: To determine if a tumor genetic characteristic, KRAS mutational status, is associated with an increased risk of VTE...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
