Impact of single versus multiple spliceosome mutations on myelodysplastic syndrome.

Abstract excerpt

Myelodysplastic syndromes (MDS) are myeloid neoplasms that are driven by genetic mutations. Generally, it is thought that a higher number of mutations is associated with worse prognosis. However, the impact of genetic mutations when they occur in the same functional class has not been well studied. Here we investigated the impact of multiple spliceosome mutations on prognosis in MDS patients, hypothesizing that...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Databases, Factual
• Share to Mutation
• Share to Myelodysplastic Syndromes