Article
Association of CTLA-4 and TNF-α polymorphism with recurrent miscarriage among North Indian women.
Cytokine - 1 Nov 2012
Gupta Rekha, Prakash Swayam, Parveen Farah, Agrawal Suraksha
Abstract excerpt
CONTEXT: CTLA-4 is engaged on effector cells that may alter signal transduction and subsequently cytokine production. The transmission of longer repeats of (AT)(n) alleles of CTLA-4 is also associated with women undergoing recurrent miscarriage. The TNF-α known as an embryo-toxic cytokine is reported to be greater in placentas of abortion prone pregnancies. OBJECTIVES: The present study investigated the role of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
