Article
Tumor necrosis factor-alpha polymorphisms in women with idiopathic recurrent miscarriage.
Journal of reproductive immunology - 1 Mar 2010
Finan R R, Al-Irhayim Z, Mustafa F E, Al-Zaman I, Mohammed F A, Al-Khateeb G M, Madan S, Issa A A, Almawi W Y
Abstract excerpt
We investigated the association of tumor necrosis factor-alpha (TNFalpha) gene polymorphisms with idiopathic recurrent miscarriage (RM). TNFalpha -1031T/C, -863C/A, -857C/T, -376G/A, -308G/A, -238G/A, and +488G/A single nucleotide polymorphisms (SNPs) were investigated in 204 RM women and 248 age-matched parous women by PCR-restriction fragment length polymorphism. Significantly higher frequencies of -1031C and...
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