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EBV and 1q Gains Affect Gene and miRNA Expression in Burkitt Lymphoma

25 Aug 2023

Abstract excerpt

Abnormalities of the long arm of chromosome 1 (1q) represent the most frequent secondary chromosomal aberrations in Burkitt lymphoma (BL) and are observed almost exclusively in EBV-negative BL cell lines (BL-CLs). To verify chromosomal abnormalities, we cytogenetically investigated EBV-negative BL patient material, and to elucidate the 1q gain impact on gene expression, we performed qPCR with six 1q-resident...

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PMID: 37766215
DOI: 10.3390/v15091808

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