Article
Yeast Lsm Pro-Apoptotic Mutants Show Defects in Autophagy.
International journal of molecular sciences - 5 Sept 2023
Caraba Benedetta, Stirpe Mariarita, Palermo Vanessa, Vaccher Ugo, Bianchi Michele Maria, Falcone Claudio, Mazzoni Cristina
Abstract excerpt
LSM4 is an essential yeast gene encoding a component of different LSM complexes involved in the regulation of mRNA splicing, stability, and translation. In previous papers, we reported that the expression in S. cerevisiae of the K. lactis LSM4 gene lacking the C-terminal Q/N-rich domain in an Lsm4 null strain S. cerevisiae (Sclsm4Δ1) restored cell viability. Nevertheless, in this transformed strain, we observed...
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