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Article

Huntington's disease: how intermediate are intermediate repeat lengths?

Movement disorders : official journal of the Movement Disorder Society - 1 Dec 2012

Squitieri Ferdinando, Jankovic Joseph

Abstract excerpt

BACKGROUND: Huntington's disease (HD) is a devastating heredoneurodegenerative disorder associated with a wide variety of neurological and psychiatric symptoms caused by an expanded CAG repeat in the HTT gene. The expansion mutation in HTT is dominantly transmitted and codes for a protein named huntingtin (htt). HYPOTHESIS: One hypothesis, according to a multistep mechanism, is that the intergenerational...

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Source

Identifiers

PMID: 23008174
DOI: 10.1002/mds.25172

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Huntington's disease: how intermediate are intermediate repeat lengths?PMID 23008174Read ↗

Is There Convincing Evidence that Intermediate Repeats in the HTT Gene Cause Huntington's Disease?Semantic proximity Read ↗

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Intermediate CAG repeats in Huntington‘s Disease: Analysis of COHORTSemantic proximity Read ↗

Evidence‐based genetic counselling implications for Huntington disease intermediate allele predictive test resultsSemantic proximity Read ↗

Exploring the correlates of intermediate CAG repeats in Huntington disease.Semantic proximity Read ↗

CAG size-specific risk estimates for intermediate allele repeat instability in Huntington disease.Semantic proximity Read ↗

Late-onset Huntington disease with intermediate CAG repeats: true or false?Semantic proximity Read ↗

Predictive testing for Huntington disease: interpretation and significance of intermediate alleles.Semantic proximity Read ↗

Molecular analysis of new mutations for Huntington's disease: intermediate alleles and sex of origin effects.Semantic proximity Read ↗

Increased instability of intermediate alleles in families with sporadic Huntington disease compared to similar sized intermediate alleles in the general population.Semantic proximity Read ↗

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