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Article

Causal association between peripheral immune cells and IgA nephropathy: a Mendelian randomization study.

Frontiers in immunology - 1 Jan 2024

Liang Li-Mei, Xiong Liang, He Xin-Liang, Song Lin-Jie, Wang Xiaorong, Lu Yu-Zhi, Ye Hong, Ma Wan-Li, Yu Fan

Abstract excerpt

Background: The relationship between peripheral immune cells and immunoglobulin A nephropathy (IgAN) is widely known; however, causal evidence of this link is lacking. Here, we aimed to determine the causal effect of peripheral immune cells, specifically total white blood cells, lymphocytes, monocytes, basophils, eosinophils, and neutrophils, as well as lymphocyte subset traits, on the IgAN risk using a Mendelian...

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CRP gene
Genetic Predisposition to Disease
Genome-Wide Association Study
Glomerulonephritis, IGA
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 39221249
DOI: 10.3389/fimmu.2024.1371662
PMCID: PMC11361932

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CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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