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Article

Using a novel structure/function approach to select diverse swine major histocompatibility complex 1 alleles to predict epitopes for vaccine development.

Bioinformatics (Oxford, England) - 3 Oct 2023

Khatooni Zahed, Teymourian Navid, Wilson Heather L

Abstract excerpt

MOTIVATION: Swine leukocyte antigens (SLAs) (i.e. swine major histocompatibility complex proteins) conduct a fundamental role in swine immunity. To generate a protective vaccine across an outbred species, such as pigs, it is critical that epitopes that bind to diverse SLA alleles are used in the vaccine development process. We introduced a new strategy for epitope prediction. RESULTS: We employed molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37740287
DOI: 10.1093/bioinformatics/btad590
PMCID: PMC10551226

Genes

SLA

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