Article
Development and validation of an epitope prediction tool for swine (PigMatrix) based on the pocket profile method.
BMC bioinformatics - 15 Sept 2015
Gutiérrez Andres H, Martin William D, Bailey-Kellogg Chris, Terry Frances, Moise Leonard, De Groot Anne S
Abstract excerpt
BACKGROUND: T cell epitope prediction tools and associated vaccine design algorithms have accelerated the development of vaccines for humans. Predictive tools for swine and other food animals are not as well developed, primarily because the data required to develop the tools are lacking. Here, we overcome a lack of T cell epitope data to construct swine epitope predictors by systematically leveraging available...
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