Article
Development and characterization of monoclonal antibodies against the N-terminal domain of African swine fever virus structural protein, p54.
International journal of biological macromolecules - 1 Jun 2021
Wang Aiping, Jiang Min, Liu Hongliang, Liu Yankai, Zhou Jingming, Chen Yumei, Ding Peiyang, Wang Yanwei, Pang Weisheng, Qi Yanhua, Zhang Gaiping
Abstract excerpt
African swine fever virus (ASFV), a re-emerging DNA virus, causes a highly contagious disease for domestic pigs. It is running rife worldwide and threatening the global swine industry. Protein p54 is an attractive candidate for ASFV diagnostic and vaccine design. In this work, we designed a peptide to mimic the N-terminal domain (NTD) of ASFV p54 and pretested it with sera from ASFV-infected pigs. The peptide...
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