From structure prediction to function: defining the domain on the African swine fever virus CD2v protein required for binding to erythrocytes

Abstract excerpt

ABSTRACT African swine fever virus (ASFV) is a high-consequence pathogen posing a substantial threat to global food security. This large DNA virus encodes more than 150 open reading frames, many of which are uncharacterized. The EP402R gene encodes CD2v, a glycoprotein expressed on the surface of infected cells and the only viral protein known to be present in the virus external envelope. This protein mediates...