Article
Insight into the relationship between resting heart rate and atrial fibrillation: a Mendelian randomization study.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology - 5 Oct 2023
Klevjer Marie, Rasheed Humaira, Romundstad Pål R, Madssen Erik, Brumpton Ben M, Bye Anja
Abstract excerpt
AIMS: A low resting heart rate (RHR) implies a more efficient heart function and a lower risk of cardiovascular disease. However, observational studies have reported a U-shaped association between RHR and atrial fibrillation (AF). In contrast, Mendelian randomization (MR) studies have found an inverse causal association between RHR and AF. Hence, the causal nature of the relationship is not clear. The aim is to...
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