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Mevalonate pathway and male reproductive aging

21 Sept 2023

Abstract excerpt

Male fertility declines with age. The mevalonate pathway, through which cholesterol and nonsteroidal isoprenoids are synthesized, plays key role in metabolic processes and is an essential pathway for cholesterol production and protein prenylation. Male reproductive aging is accompanied by dramatic changes in the metabolic microenvironment of the testis. Since the mevalonate pathway has an important role in...

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PMID: 37733694
DOI: 10.1002/mrd.23705

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