Article
Characterisation of IL ‐1 family members in Sweet syndrome highlights the overexpression of IL ‐1β and IL‐1R3 as possible therapeutic targets
19 Sept 2023
Abstract excerpt
Sweet syndrome (SS) as a prototypic neutrophilic dermatosis (NDs) shares certain clinical and histologic features with monogenic auto-inflammatory disorders in which interleukin (IL)-1 cytokine family members play an important role. This has led to the proposal that NDs are polygenic auto-inflammatory diseases and has fuelled research to further understand the role of IL-1 family members in the pathogenesis of...
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