Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-10b-5p rescues leaky gut linked with gastrointestinal dysmotility and diabetes.

United European gastroenterology journal - 1 Oct 2023

Zogg Hannah, Singh Rajan, Ha Se Eun, Wang Zhuqing, Jin Byungchang, Ha Mariah, Dafinone Mirabel, Batalon Tylar, Hoberg Nicholas, Poudrier Sandra, Nguyen Linda, Yan Wei, Layden Brian T, Dugas Lara R, Sanders Kenton M, Ro Seungil

Abstract excerpt

BACKGROUND/AIM: Diabetes has substantive co-occurrence with disorders of gut-brain interactions (DGBIs). The pathophysiological and molecular mechanisms linking diabetes and DGBIs are unclear. MicroRNAs (miRNAs) are key regulators of diabetes and gut dysmotility. We investigated whether impaired gut barrier function is regulated by a key miRNA, miR-10b-5p, linking diabetes and gut dysmotility. METHODS: We created...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Barrier Structure and Function Studies
Share to Diabetes Mellitus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastrointestinal motility and disorders

Share to Gut microbiota and health

Share to Irritable Bowel Syndrome

Share to MicroRNAs

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 37723933
DOI: 10.1002/ueg2.12463
PMCID: PMC10576606

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR-10b-5p rescues leaky gut linked with gastrointestinal dysmotility and diabetes.PMID 37723933Read ↗

Role of microRNAs in Disorders of Gut–Brain Interactions: Clinical Insights and Therapeutic AlternativesSemantic proximity Read ↗

Loss of claudin-3 expression increases colitis risk by promoting Gut DysbiosisSemantic proximity Read ↗

MYO5B gene mutations may promote the occurrence of very early onset inflammatory bowel disease: a case report.Semantic proximity Read ↗

Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetesSemantic proximity Read ↗

The miR-200–Zeb1 axis regulates key aspects of β-cell function and survival in vivoSemantic proximity Read ↗

Gut Microbiota Dysbiosis Drives Myocardial Hypertrophy Through GBP2b/GBP1-Mediated Immune Reprogramming and Exosomal Signaling in Chronic ColitisSemantic proximity Read ↗

Similarities and differences in constipation phenotypes between Lep knockout mice and high fat diet-induced obesity mice.Semantic proximity Read ↗

JAM-A regulates permeability and inflammation in the intestine in vivo.Semantic proximity Read ↗

Gut-associated cGMP mediates colitis and dysbiosis in a mouse model of an activating mutation in GUCY2C.Semantic proximity Read ↗

Recent advances in vasoactive intestinal peptide physiology and pathophysiology: focus on the gastrointestinal systemSemantic proximity Read ↗

MicroRNA 29 targets nuclear factor-κB-repressing factor and Claudin 1 to increase intestinal permeability.Semantic proximity Read ↗

miR-16 and miR-125b are involved in barrier function dysregulation through the modulation of claudin-2 and cingulin expression in the jejunum in IBS with diarrhoeaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.