Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heterogeneous response to TGF-β1/3 isoforms in fibroblasts of different origins: implications for wound healing and tumorigenesis

14 Sept 2023

Abstract excerpt

Identification of therapeutic targets for treating fibrotic diseases and cancer remains challenging. Our study aimed to investigate the effects of TGF-β1 and TGF-β3 on myofibroblast differentiation and extracellular matrix deposition in different types of fibroblasts, including normal/dermal, cancer-associated, and scar-derived fibroblasts. When comparing the phenotype and signaling pathways activation we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatologic Treatments and Research
Share to Periodontal Regeneration and Treatments
Share to Wound Healing and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37707642
DOI: 10.1007/s00418-023-02221-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heterogeneous response to TGF-β1/3 isoforms in fibroblasts of different origins: implications for wound healing and tumorigenesisPMID 37707642Read ↗

Multifaceted TGF‐β signaling, a master regulator: From bench‐to‐bedside, intricacies, and complexitiesSemantic proximity Read ↗

Advances and Challenges in Targeting TGF-β Isoforms for Therapeutic Intervention of Cancer: A Mechanism-Based PerspectiveSemantic proximity Read ↗

TGF-β signaling in health and diseaseSemantic proximity Read ↗

TGF-β/TGF-β receptor system and its role in physiological and pathological conditions.Semantic proximity Read ↗

BMP1 Promotes Keloid by Inducing Fibroblast Inflammation and FibrogenesisSemantic proximity Read ↗

TGF-beta signaling: a tale of two responses.Semantic proximity Read ↗

Keloid disorder: Fibroblast differentiation and gene expression profile in fibrotic skin diseasesSemantic proximity Read ↗

Profiling Fibrosis through Single-Cell and Spatial Transcriptomics Analysis: cell identity and tissue architectureSemantic proximity Read ↗

Cellular and molecular mechanisms in fibrosisSemantic proximity Read ↗

A bird’s eye view of fibroblast heterogeneity: A pan‐disease, pan‐cancer perspectiveSemantic proximity Read ↗

Transforming growth factor beta (TGFβ) and keloid diseaseSemantic proximity Read ↗

Fibroblast heterogeneity and functions: insights from single-cell sequencing in wound healing, breast cancer, ovarian cancer and melanomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.