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Keloid disorder: Fibroblast differentiation and gene expression profile in fibrotic skin diseases

20 Nov 2020

Abstract excerpt

Keloid disorder, a group of fibroproliferative skin diseases, is characterized by unremitting accumulation of the extracellular matrix (ECM) of connective tissue, primarily collagen, to develop cutaneous tumors on the predilection sites of skin. There is a strong genetic predisposition for keloid formation, and individuals of African and Asian ancestry are particularly prone. The principal cell type responsible...

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PMID: 33211348
DOI: 10.1111/exd.14243

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