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Article

Anaplastic PXA in adults: case series with clinicopathologic and molecular features.

Journal of neuro-oncology - 1 Jan 2013

Schmidt Yao, Kleinschmidt-DeMasters B K, Aisner Dara L, Lillehei Kevin O, Damek Denise

Abstract excerpt

Pleomorphic xanthoastrocytomas with anaplastic features (PXA-As) are rare tumors about which little is known regarding clinicopathologic and molecular features. Several studies have identified BRAF V600E mutations in PXA-As, but the percentage with mutation may differ between adult and pediatric examples, and limited information exists about immunohistochemistry for isocitrate dehydrogenase 1 (IDH1). Ten cases of...

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Identifiers

PMID: 23096133
DOI: 10.1007/s11060-012-0991-4
PMCID: PMC4617340

Genes

BRAF
IDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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