Article
Actigraphic characterization of sleep and circadian phenotypes of PER3 gene VNTR genotypes.
Chronobiology international - 2 Sept 2023
Viana Mendes Juliana, Benedito-Silva Ana Amélia, Medeiros Andrade Maria Augusta, Vartanian Daniel, da Silva Brandão Gonçalves Bruno, Cipolla-Neto José, Pedrazzoli Mario
Abstract excerpt
The molecular circadian timing system involves genes known as "clock genes," such as the PER3 gene. Studies have demonstrated associations among a repeat polymorphism (VNTR) of the PER3 gene with chronotypes, with the occurrence of circadian rhythm disorders and with sleep homeostasis phenotypes. The aim of this study was to investigate, by actigraphy, sleep and circadian rhythm profiles of people with different...
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