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Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte development in the mouse telencephalon

8 Sept 2023

Abstract excerpt

Abstract Background E-proteins encoded by Tcf3, Tcf4, and Tcf12 are class I basic helix-loop-helix (bHLH) transcription factors (TFs) that are thought to be widely expressed during development. However, their function in the developing brain, specifically in the telencephalon remains an active area of research. Our study examines for the first time if combined loss of two E-proteins (Tcf3 and Tcf12) influence...

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PMID: 37684687
DOI: 10.1186/s13064-023-00173-z

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