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Article

Consensus molecular subtype transition during progression of colorectal cancer.

The Journal of pathology - 1 Nov 2023

van de Weerd Simone, Torang Arezo, Zwager Liselotte W, Koelink Pim J, Koster Jan, Bastiaansen Barbara Aj, Lammers Veerle, Longobardi Ciro, Roodhart Jeanine Ml, van Krieken J Han, Farina Sarasqueta Arantza, Dekker Evelien, Medema Jan Paul

Abstract excerpt

The consensus molecular subtype (CMS) classification divides colorectal cancer (CRC) into four distinct subtypes based on RNA expression profiles. The biological differences between CMSs are already present in CRC precursor lesions, but not all CMSs pose the same risk of malignant transformation. To fully understand the path to malignant transformation and to determine whether CMS is a fixed entity during...

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Source

Identifiers

PMID: 37681286
DOI: 10.1002/path.6176

Genes

TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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