Article
[Characterization of patients with sporadic colorectal cancer following the new Consensus Molecular Subtypes (CMS)].
Revista medica de Chile - 1 Apr 2017
Wielandt Ana María, Villarroel Cynthia, Hurtado Claudia, Simian Daniela, Zamorano Diego, Martínez Maripaz, Castro Magdalena, Vial María Teresa, Kronberg Udo, López-Kostner Francisco
Abstract excerpt
BACKGROUND: Colorectal cancer (CRC) is an heterogeneous disease. Three carcinogenic pathways determine its molecular profile: microsatellite instability (MSI), chromosomal instability (CIN) and CpG island methylator phenotype (CIMP). Based on the new molecular classification, four consensus CRC molecular subtypes (CMS) are established, which are related to clinical, pathological and biological characteristics of...
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