Article
Modeling of African population history using f-statistics is biased when applying all previously proposed SNP ascertainment schemes.
PLoS genetics - 1 Sept 2023
Flegontov Pavel, Işıldak Ulaş, Maier Robert, Yüncü Eren, Changmai Piya, Reich David
Abstract excerpt
f-statistics have emerged as a first line of analysis for making inferences about demographic history from genome-wide data. Not only are they guaranteed to allow robust tests of the fits of proposed models of population history to data when analyzing full genome sequencing data-that is, all single nucleotide polymorphisms (SNPs) in the individuals being analyzed-but they are also guaranteed to allow robust tests...
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