Legofit: Estimating Population History from Genetic Data

Abstract excerpt

<h4>Background</h4> Our current understanding of archaic admixture in humans relies on statistical methods with large biases, whose magnitudes depend on the sizes and separation times of ancestral populations. To avoid these biases, it is necessary to estimate these parameters simultaneously with those describing admixture. Genetic estimates of population histories also confront problems of statistical identifiab...

Topics

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• Evolution, Molecular
• Genetic Drift
• Genetic Variation
• Genetics, Population
• Genome-Wide Association Study
• History, Ancient
• Models, Genetic
• Racial Groups

Identifiers and source

Literature Corpus work

bb2aeaf3-9a3f-5072-a2a2-906368c3c555

DOI

10.1101/613067