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Article

Impact of signal intensity normalization of MRI on the generalizability of radiomic-based prediction of molecular glioma subtypes.

European radiology - 1 Apr 2024

Foltyn-Dumitru Martha, Schell Marianne, Rastogi Aditya, Sahm Felix, Kessler Tobias, Wick Wolfgang, Bendszus Martin, Brugnara Gianluca, Vollmuth Philipp

Abstract excerpt

OBJECTIVES: Radiomic features have demonstrated encouraging results for non-invasive detection of molecular biomarkers, but the lack of guidelines for pre-processing MRI-data has led to poor generalizability. Here, we assessed the influence of different MRI-intensity normalization techniques on the performance of radiomics-based models for predicting molecular glioma subtypes. METHODS: Preoperative MRI-data from...

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Identifiers

PMID: 37672053
DOI: 10.1007/s00330-023-10034-2
PMCID: PMC10957611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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