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Article

Improving Noninvasive Classification of Molecular Subtypes of Adult Gliomas With Diffusion-Weighted MR Imaging: An Externally Validated Machine Learning Algorithm.

Journal of magnetic resonance imaging : JMRI - 1 Oct 2023

Guo Yang, Ma Zeyu, Pei Dongling, Duan Wenchao, Guo Yu, Liu Zhongyi, Guan Fangzhan, Wang Zilong, Xing Aoqi, Guo Zhixuan, Luo Lin, Wang Weiwei, Yu Bin, Zhou Jinqiao, Ji Yuchen, Yan Dongming, Cheng Jingliang, Liu Xianzhi, Yan Jing, Zhang Zhenyu

Abstract excerpt

BACKGROUND: Genetic testing for molecular markers of gliomas sometimes is unavailable because of time-consuming and expensive, even limited tumor specimens or nonsurgery cases. PURPOSE: To train a three-class radiomic model classifying three molecular subtypes including isocitrate dehydrogenase (IDH) mutations and 1p/19q-noncodeleted (IDHmut-noncodel), IDH wild-type (IDHwt), IDH-mutant and 1p/19q-codeleted...

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Algorithms
Brain Neoplasms
Glioma
Isocitrate Dehydrogenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Magnetic Resonance Imaging

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PMID: 36727433
DOI: 10.1002/jmri.28630

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