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Loss of Pla2r1 decreases cellular senescence and age‐related alterations caused by aging and Western diets

4 Sept 2023

Abstract excerpt

Cellular senescence is induced by many stresses including telomere shortening, DNA damage, oxidative, or metabolic stresses. Senescent cells are stably cell cycle arrested and they secrete many factors including cytokines and chemokines. Accumulation of senescent cells promotes many age-related alterations and diseases. In this study, we investigated the role of the pro-senescent phospholipase A2 receptor 1...

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PMID: 37667516
DOI: 10.1111/acel.13971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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