Article
Natural positive selection and north-south genetic diversity in East Asia.
European journal of human genetics : EJHG - 1 Jan 2012
Suo Chen, Xu Haiyan, Khor Chiea-Chuen, Ong Rick Th, Sim Xueling, Chen Jieming, Tay Wan-Ting, Sim Kar-Seng, Zeng Yi-Xin, Zhang Xuejun, Liu Jianjun, Tai E-Shyong, Wong Tien-Yin, Chia Kee-Seng, Teo Yik-Ying
Abstract excerpt
Recent reports have identified a north-south cline in genetic variation in East and South-East Asia, but these studies have not formally explored the basis of these clinical differences. Understanding the origins of these variations may provide valuable insights in tracking down the functional variants in genomic regions identified by genetic association studies. Here we investigate the genetic basis of these...
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