Article
Mendelian randomization analysis identified genes pleiotropically associated with the risk and prognosis of COVID-19.
The Journal of infection - 1 Jan 2021
Liu Di, Yang Jingyun, Feng Bowen, Lu Wenjin, Zhao Chuntao, Li Lizhuo
Abstract excerpt
OBJECTIVES: COVID-19 has caused a large global pandemic. Patients with COVID-19 exhibited considerable variation in disease behavior. Pervious genome-wide association studies have identified potential genetic variants involved in the risk and prognosis of COVID-19, but the underlying biological interpretation remains largely unclear. METHODS: We applied the summary data-based Mendelian randomization (SMR) method...
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