Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A unique case of rectal cancer with coexistence of multiple pathways of carcinogenesis.

World journal of surgical oncology - 1 Sept 2023

Rateria Nisha, Ojha Ritu, Shukla Mridula, Pandey Manoj

Abstract excerpt

BACKGROUND: Colorectal cancer with a global incidence of 10% has multiple pathways implicated in its carcinogenesis. WNT signaling is the principal underlying pathway via APC gene, while defective mismatch repair genes and epigenetic changes also are known to contribute. CASE PRESENTATION: Here, we present an unusual case of rectal adenocarcinoma in a woman, with germline MSH6 and PMS1 mutations, and simultaneous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogenesis
Share to DNA Mismatch Repair
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Rectal Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 37658412
DOI: 10.1186/s12957-023-03157-9
PMCID: PMC10472638

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A unique case of rectal cancer with coexistence of multiple pathways of carcinogenesis.PMID 37658412Read ↗

A Unique Case of Rectal Cancer with Coexistence of Multiple Pathways of CarcinogenesisSemantic proximity Read ↗

Multiple Primary Malignancies Associated with Colorectal Cancer: A Review of Clinical Features, Etiology, and PrognosisSemantic proximity Read ↗

Differential colorectal carcinogenesis: Molecular basis and clinical relevanceSemantic proximity Read ↗

Colorectal cancer in Lynch syndrome associated with PMS2 and MSH6 mutations.Semantic proximity Read ↗

A comparison of colon and rectal somatic DNA alterations.Semantic proximity Read ↗

An Insight Into the Driver Mutations and Molecular Mechanisms Underlying Mucinous Adenocarcinoma of the Rectum.Semantic proximity Read ↗

Synchronous Colorectal Carcinoma: Three Cases Report and Literature ReviewSemantic proximity Read ↗

Lynch syndrome and sextuple primary malignancies.Semantic proximity Read ↗

MLH1, BRAF and p53 - searching for significant markers to predict evolution towards adenocarcinoma in colonic sessile serrated lesions.Semantic proximity Read ↗

The genetic alterations of rectal neuroendocrine tumor and indications for therapy and prognosis: a systematic review.Semantic proximity Read ↗

Synchronous adenocarcinoma of the endometrium and colon in a woman with Lynch syndrome associated with a mutation of the MSH6 gene.Semantic proximity Read ↗

[Difference analysis of somatic mutations between deficient mismatch repair and proficient mismatch repair gene related with colorectal cancer].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.