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Article

Polygenic overlap and shared genomic loci between anorexia nervosa and cardiometabolic traits suggest shared biological mechanisms.

Neurobiology of disease - 1 Sept 2026

Lu Zheng-An, Ploner Alexander, Birgegård Andreas, Bergen Sarah E

Abstract excerpt

BACKGROUND: Anorexia nervosa (AN) is a serious psychiatric disorder with prominent metabolic features. Although extensive AN-metabolic genetic correlations have been observed, few studies have thoroughly investigated their shared genetic mechanisms. Based on large-scale genome-wide association studies, this study examines the shared genetic architecture between AN and seven common cardiometabolic traits (body...

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PMID: 42276302
DOI: 10.1016/j.nbd.2026.107476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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