Article
Influence of obesity on association between genetic variants identified by genome-wide association studies and hypertension risk in Chinese children.
American journal of hypertension - 1 Aug 2013
Xi Bo, Zhao Xiaoyuan, Chandak Giriraj R, Shen Yue, Cheng Hong, Hou Dongqing, Wang Xingyu, Mi Jie
Abstract excerpt
BACKGROUND: Childhood hypertension is a complex disease influenced by both genetic and environmental factors. We aimed to examine how obesity status influences the association of 6 single nucleotide polymorphisms (SNPs) identified by genome-wide association studies (GWASs) with systolic/diastolic blood pressure (SBP/DBP) and hypertension in Chinese children. METHODS: We recruited 619 hypertensive case subjects...
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