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Article

A CRISPR-Cas12a-Based Diagnostic Method for Japanese Encephalitis Virus Genotypes I, III, and V.

Biosensors - 28 Jul 2023

Kwak Namki, Park Bum Ju, Song Yoon-Jae

Abstract excerpt

The Japanese encephalitis virus (JEV) is prevalent in Asian countries, including Korea, Japan, China, Vietnam, and India. JEV is transmitted to humans by Culex mosquitoes. Despite extensive research efforts, no approved antiviral agents are currently available, although JE can be prevented by vaccination. DNA endonuclease-targeted CRISPR trans reporter (DETECTR) is a newly emerging CRISPR-Cas12a-based molecular...

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Identifiers

PMID: 37622855
DOI: 10.3390/bios13080769
PMCID: PMC10452572

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