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Article

Sex-specific transgenerational effects of preconception exposure to arsenite: metabolic phenotypes of C57BL/6 offspring.

Archives of toxicology - 1 Nov 2023

Shang Bingzhen, Venkatratnam Abhishek, Liu Tianyi, Douillet Christelle, Shi Qing, Miller Madison, Cable Peter, Zou Fei, Ideraabdullah Folami Y, Fry Rebecca C, Stýblo Miroslav

Abstract excerpt

Chronic exposure to inorganic arsenic (iAs) has been linked to diabetes in both humans and mice, but the role of iAs exposure prior to conception and its transgenerational effects are understudied. The present study investigated transgenerational effects of preconception iAs exposure in C57BL/6J mice, focusing on metabolic phenotypes of G1 and G2 offspring. Body composition and diabetes indicators, including...

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Identifiers

PMID: 37615676
DOI: 10.1007/s00204-023-03582-5
PMCID: PMC10754030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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