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Article

Bisphenol A Exposure Disrupts Metabolic Health Across Multiple Generations in the Mouse

25 Mar 2015

Abstract excerpt

Accumulating evidence has suggested that a suboptimal early life environment produces multigenerational developmental defects. A proposed mechanism is stable inheritance of DNA methylation. Here we show that maternal bisphenol A (BPA) exposure in C57BL/6 mice produces multigenerational metabolic phenotypes in their offspring. Using various methods including dual-energy X-ray absorptiometry analyses, glucose...

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PMID: 25807043
DOI: 10.1210/en.2014-2027

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