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Article

EnzyHTP Computational Directed Evolution with Adaptive Resource Allocation.

Journal of chemical information and modeling - 11 Sept 2023

Shao Qianzhen, Jiang Yaoyukun, Yang Zhongyue J

Abstract excerpt

Directed evolution facilitates enzyme engineering via iterative rounds of mutagenesis. Despite the wide applications of high-throughput screening, building "smart libraries" to effectively identify beneficial variants remains a major challenge in the community. Here, we developed a new computational directed evolution protocol based on EnzyHTP, a software that we have previously reported to automate enzyme...

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Identifiers

PMID: 37611241
DOI: 10.1021/acs.jcim.3c00618
PMCID: PMC11211066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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