Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Efficacy of antiviral therapy and host–virus interactions visualised using serial liver sampling with fine-needle aspirates

19 Jun 2023

Abstract excerpt

Background & Aims: Novel therapies for chronic hepatitis B (CHB), such as RNA interference, target all viral RNAs for degradation, whereas nucleoside analogues are thought to block reverse transcription with minimal impact on viral transcripts. However, limitations in technology and sampling frequency have been obstacles to measuring actual changes in HBV transcription in the liver of patients starting therapy....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Hepatitis C virus research
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37600958
DOI: 10.1016/j.jhepr.2023.100817

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Efficacy of antiviral therapy and host–virus interactions visualised using serial liver sampling with fine-needle aspiratesPMID 37600958Read ↗

Single-cell RNA sequencing of liver fine-needle aspirates captures immune diversity in the blood and liver in chronic hepatitis B patientsSemantic proximity Read ↗

Liver-specific Inflammatory Signatures Predict Clinically Significant Liver DamageSemantic proximity Read ↗

Pathogenic CD8 T cells defined by longitudinal liver sampling in chronic hepatitis B patients starting antiviral therapySemantic proximity Read ↗

Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elementsSemantic proximity Read ↗

Spatial transcriptomics links hepatocyte-macrophage interactions to viral signatures in seronegative hepatitisSemantic proximity Read ↗

Single-Molecule Sequencing Reveals Complex Genome Variation of Hepatitis B Virus during 15 Years of Chronic Infection following Liver Transplantation.Semantic proximity Read ↗

Hepatitis B virus serum RNA transcript isoform composition and proportion in chronic hepatitis B patients by nanopore long-read sequencingSemantic proximity Read ↗

Liver-resident CD8+ T cells in viral hepatitis: not always good guysSemantic proximity Read ↗

Second-Phase Hepatitis C Plasma Viral Kinetics Directly Reflects Reduced Intrahepatic Burden of Hepatitis C Virus.Semantic proximity Read ↗

Interferon lambda alleles predict innate antiviral immune responses and hepatitis C virus permissiveness.Semantic proximity Read ↗

Viral expression and molecular profiling in liver tissue versus microdissected hepatocytes in hepatitis B virus - associated hepatocellular carcinomaSemantic proximity Read ↗

Mapping the Heterogeneity of Histone Modifications on Hepatitis B Virus DNA Using Liver Needle Biopsies Obtained from Chronically Infected PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.