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Article

Principal component analysis of a swine injury model identifies multiple phenotypes in trauma.

The journal of trauma and acute care surgery - 1 Apr 2024

Buzzard Lydia, Smith Sawyer, Dixon Alexandra, Kenny James, Appleman Ma, Subramanian Sarayu, Behrens Brandon, Rick Elizabeth, Madtson Brianne, Goodman Andrew, Murphy James, McCully Belinda, Kanlerd Amonpon, Trivedi Alpa, Pati Shibani, Schreiber Martin

Abstract excerpt

BACKGROUND: Trauma is the third leading cause of death in the United States and the primary cause of death for people between the ages of 1 year and 44 years. In addition to tissue damage, trauma may also activate an inflammatory state known as trauma-induced coagulopathy (TIC) that is associated with clotting malfunctions, acidemia, and end-organ dysfunction. Prior work has also demonstrated benefit to...

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PMID: 37599420
DOI: 10.1097/TA.0000000000004098

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