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Article

Serotonergic multilocus genetic variation moderates the association between interpersonal relationship and adolescent depressive symptoms.

Journal of affective disorders - 1 Nov 2023

Zeng Zihao, Peng Liyi, Liu Shuangjin, Yang Qin, Wang Hongcai, He Zhen, Hu Yiqiu

Abstract excerpt

BACKGROUND: Research suggests that genetic variants linked to serotonin functioning moderate the association between environmental stressors and depressive symptoms, but examining gene-environment interactions with single polymorphisms limits power. METHODS: A multilocus genetic profile score (MGPS) approach to measuring serotonergic multilocus genetic variation and examined interactions with interpersonal...

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PMID: 37597782
DOI: 10.1016/j.jad.2023.08.085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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