Article
HPA axis multilocus genetic profile score moderates the impact of interpersonal stress on prospective increases in depressive symptoms for offspring of depressed mothers.
Journal of abnormal psychology - 1 Nov 2017
Feurer Cope, McGeary John E, Knopik Valerie S, Brick Leslie A, Palmer Rohan H, Gibb Brandon E
Abstract excerpt
Although offspring of depressed mothers are at an increased risk for depression themselves, not all of these children develop depression, highlighting the need to identify specific environmental and genetic moderators of risk. The goal of this study was to examine the aggregate influence of genetic polymorphisms associated with the regulation of the hypothalamic-pituitary-adrenal (HPA) axis as a potential...
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