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Article

Excessive Thyroid Hormone Signaling Induces Photoreceptor Degeneration in Mice

18 Aug 2023

Abstract excerpt

Abstract Rod and cone photoreceptors degenerate in inherited and age-related retinal degenerative diseases, ultimately leading to loss of vision. Thyroid hormone (TH) signaling regulates cell proliferation, differentiation, and metabolism. Recent studies have shown a link between TH signaling and retinal degeneration. This work investigates the effects of excessive TH signaling on photoreceptor function and...

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Identifiers

PMID: 37596046
DOI: 10.1523/eneuro.0058-23.2023

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