Article
ZFP36 loss-mediated BARX1 stabilization promotes malignant phenotypes by transactivating master oncogenes in NSCLC.
Cell death & disease - 16 Aug 2023
Zhang Tongjia, Qiu Lizhen, Cao Jiashun, Li Qiu, Zhang Lifan, An Guoshun, Ni Juhua, Jia Hongti, Li Shuyan, Li Kailong
Abstract excerpt
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, with high morbidity and mortality worldwide. Although the dysregulation of BARX1 expression has been shown to be associated with malignant cancers, including NSCLC, the underlying mechanism remains elusive. In this study, we identified BARX1 as a common differentially expressed gene in lung squamous cell carcinoma and adenocarcinoma....
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