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miR-30e-5p regulates leukemia stem cell self-renewal through the Cyb561/ROS signaling pathway

16 Aug 2023

Abstract excerpt

Leukemia stem cells (LSC) represent a crucial and rare subset of cells present in acute myeloid leukemia (AML); they play a pivotal role in the initiation, maintenance, and relapse of this disease. Targeting LSC holds great promise for preventing AML relapse and improving long-term outcomes. However the precise molecular mechanisms governing LSC self-renewal are still poorly understood. Here, we present...

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PMID: 37584287
DOI: 10.3324/haematol.2023.282837

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