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Article

REPTOR and CREBRF encode key regulators of muscle energy metabolism

15 Aug 2023

Abstract excerpt

Metabolic flexibility of muscle tissue describes the adaptive capacity to use different energy substrates according to their availability. The disruption of this ability associates with metabolic disease. Here, using a Drosophila model of systemic metabolic dysfunction triggered by yorkie-induced gut tumors, we show that the transcription factor REPTOR is an important regulator of energy metabolism in muscles. We...

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PMID: 37582831
DOI: 10.1038/s41467-023-40595-1

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